Hey all! I am Yanran Liu, a PhD student at the Department of Biomedical Sciences, City University of Hong Kong(香港城市大学). If you are seeking any form of academic cooperation, please feel free to email me at yanranliu7-c@my.cityu.edu.hk.

  • 🎓 I will be joining the CompBioClub in September 2026, under the supervision of Prof. Lingxi CHEN (陈凌曦).

  • 🔬 Currently, I am a Visiting Student Researcher at the School of Information Science and Technology, Great Bay University, supervised by Prof. Xubin ZHENG (郑旭彬).

  • 📚 I received my M.Sc. in Information Systems from City University of Hong Kong and my B.Eng. in Financial Engineering from Dalian Maritime University.

🔍 Research Interests

My research interests mainly include AI for Biomedical Science and Bioinformatics, specifically in:

  • Spatial Multi-omics
  • AI in Healthcare
  • Online Biomedical Platforms

🔥 News

  • 2026.02:  🎉 Our work on influenza prediction has been published in BMC Public Health!
  • 2025.11:  🚀 Huge news! Our spatial multi-omics model, GROVER, has been accepted by AAAI 2026!
  • 2025.10:  🎊 Triple win at BIBM 2025! Thrilled to announce that our work BioLinkGPT is headed to BIBM 2025!
  • 2025.10:  ✨ Our project SVP has also been accepted by BIBM 2025!
  • 2025.10:  � Another win! Our gene regulatory relationship prediction model has been accepted by BIBM 2025.
  • 2025.10:  🎓🥳 Celebrated my Master’s graduation at CityU HK! A wonderful journey comes to an end!
  • 2024.12:  🎉 Our first spatial multi-omics model, PRAGA, was accepted by AAAI 2025!
  • 2024.12:  ✨ Back to the research frontline at GBU!
  • 2024.09:  🎓 A new chapter begins! Officially started my Master’s journey at CityU HK.
  • 2024.08:  👋 Temporarily bidding farewell to GBU. New adventures await!
  • 2024.04:  ⚓ Joined Great Bay University (GBU). This is where my research dream officially sets sail!

📝 Publications

BIBM 2025
sym

Predicting Gene Regulatory Relationship in Cancer Using LLM and Graph Neural Network from Known Regulations

Yanran Liu, Dian Meng, Xinlei Huang, Yidi Wang, et al.

BIBM 2025(CCF-B Conference)

  • Extracted gene regulatory relationships from 31,000+ PubMed abstracts using LLM to construct cancer-specific networks.
  • Applied Magnetic Signed GNN for link prediction to discover novel regulatory relationships.
  • Achieved SOTA performance with predictions validated by external cell line data.
BMC Public Health
sym

Two-Stage Hybrid Model for Influenza Trend Forecasting and Key Driver Analysis

Yanran Liu, Jingxia Guo, Xubin Zheng, et al.

BMC Public Health(JCR Q1 Journal)

  • Analyzed 2011-2023 influenza data in Xinjiang with demographic and virological drivers across pre/post-COVID periods.
  • Developed LSTM-GBR hybrid model integrating key drivers via systematic feature engineering.
  • Identified school-age cases and viral strain proportions as primary predictors of outbreak severity.
AAAI 2025
sym

PRAGA: Prototype-aware Graph Adaptive Aggregation for Spatial Multi-modal Omics Analysis

Xinlei Huang, Zhiqi Ma, Dian Meng, Yanran Liu, et al.

AAAI 2025(CCF-A Conference)

  • Proposed dynamic graph construction to capture latent semantic relations that fixed KNN graphs fail to model due to sequencing perturbations.
  • Designed cross-modal learning module to integrate spatial information and denoise perturbations from sequencing.
  • Introduced Bayesian GMM-based prototype contrastive learning to optimize representations without known class priors, achieving SOTA over 7 baselines.
  • AAAI 2026 GROVER: Graph-guided Representation of Omics and Vision with Expert Regulation for Adaptive Spatial Multi-omics Fusion, Yongjun Xiao, Dian Meng, Xinlei Huang, Yanran Liu, et al.
  • BIBM 2025 SVP: Support Vector Gene Pair as Biomarker Selection for Breast Cancer, Yijun Zhou, Qiyi Chen, Dian Meng, Yanran Liu, Jinchao Feng, Xubin Zheng.
  • BIBM 2025 BioLinkGPT: Predicting Missing TF-target Gene Interactions Using Graph Neural Networks with Large Language Model, Zhihua Du, Weiliang Huang, Yanran Liu, et al.